CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
A nuclear pore component regulates select p53 target genes
DOI 10.1055/s-0031-1296009
Bibliografische Angaben
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Autor:innenSR Singer, A Barsotti, M Fazollahi, A Ouwehand, D Grünwald, K Breuhahn, H Bussemaker, R Singer, P Schirmacher, C Prives
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Alhough many studies have focused on specific transcriptional programs regulated by p53 in response to different stresses, p53 target gene preference is still poorly defined and may rely on additional modes of regulation. Here, we demonstrate that the nucleoporin Nup98 is required for full expression of key effectors of the p53 pathway, such as p21, by a process that occurs post-transcriptionally. Nup98 associates w…
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Zitierempfehlung
SR Singer, A Barsotti, M Fazollahi, A Ouwehand, D Grünwald, K Breuhahn, H Bussemaker, R Singer, P Schirmacher, C Prives (2012) A nuclear pore component regulates select p53 target genes. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1296009
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