CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Role of the transcription factor c-Jun/AP–1 in response to β-Catenin signaling in the liver
DOI 10.1055/s-0031-1296015
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Autor:innenC Trierweiler, K Willim, HE Blum, P Hasselblatt
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background & Aims: The Wnt/β-Catenin signaling pathway is important in liver physiology and frequently deregulated in hepatocellular carcinoma. Analysis of the immediate hepatic phenotypes and molecular events following β-Catenin activation e.g. by deletion of the tumor suppressor APC may therefore identify novel candidates for targeted therapies. The AP–1 transcription factor c-Jun is considered as a β-Catenin targ…
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Zitierempfehlung
C Trierweiler, K Willim, HE Blum, P Hasselblatt (2012) Role of the transcription factor c-Jun/AP–1 in response to β-Catenin signaling in the liver. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1296015
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