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Altered autophagy in Hermansky-Pudlak syndrome associated interstitial pneumonia

S Ahuja, C Ruppert, I Henneke, B Gochuico, M Korfei, W Seeger, A Guenther, P Mahavadi · Pneumologie · Ausgabe 12/2011

DOI 10.1055/s-0031-1296092

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Autor:innenS Ahuja, C Ruppert, I Henneke, B Gochuico, M Korfei, W Seeger, A Guenther, P Mahavadi
ZeitschriftPneumologie
Ausgabe12/2011
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: Autophagy is a self-destructive, lysosomal catabolic pathway and is known from several decades as an adaptation to starvation. Basal autophagy is extremely important in turn-over of long lived proteins. Defective or severely altered macroautophagy has been reported and has been implicated in the pathogenesis of many lysosome related disorders. Hermansky-Pudlak syndrome (HPS) is one such lysosome realat…

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Zitierempfehlung

S Ahuja, C Ruppert, I Henneke, B Gochuico, M Korfei, W Seeger, A Guenther, P Mahavadi (2011) Altered autophagy in Hermansky-Pudlak syndrome associated interstitial pneumonia. Pneumologie (12). https://doi.org/10.1055/s-0031-1296092

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