CareLit · DOI-Nachweis · Pneumologie
Role of the macrophage-inducible C-type lectin Mincle in the lung host defense against mycobacterial infections in mice
DOI 10.1055/s-0031-1296095
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Nachweis in CareLit
Autor:innenF Behler, K Steinwede, R Maus, J Bohling, UA Maus
ZeitschriftPneumologie
Ausgabe12/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: The macrophage-inducible C-type lectin Mincle has been shown to serve as a receptor for the mycobacterial cell wall component trehalose dimycolate (TDM, cord factor) of M. tuberculosis. Mincle is associated with FcRγ, an immunoreceptor tyrosine-based activation motif (ITAM)-containing adaptor. Therefore, Mincle expressed on activated macrophages may serve to fine-tune innate immune responses of the lun…
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Zitierempfehlung
F Behler, K Steinwede, R Maus, J Bohling, UA Maus (2011) Role of the macrophage-inducible C-type lectin Mincle in the lung host defense against mycobacterial infections in mice. Pneumologie (12). https://doi.org/10.1055/s-0031-1296095
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