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Prolonged Development of Elastase-Induced Emphysema is Supported by Increased Apoptosis

A Bohla, K Kohse, O Eickelberg, AÖ Yildirim · Pneumologie · Ausgabe 12/2011

DOI 10.1055/s-0031-1296099

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Autor:innenA Bohla, K Kohse, O Eickelberg, AÖ Yildirim
ZeitschriftPneumologie
Ausgabe12/2011
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: Chronic obstructive pulmonary disease (COPD), one of the leading causes of death worldwide, is characterized amongst others by development of emphysema, which is known to occur as a result of imbalance of proteases and antiproteases. There are a variety of enzymes like neutrophil elastase (NE) and matrix metalloprotease 12 (MMP-12), which are capable of destroying parenchymal tissue, causing loss of al…

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Zitierempfehlung

A Bohla, K Kohse, O Eickelberg, AÖ Yildirim (2011) Prolonged Development of Elastase-Induced Emphysema is Supported by Increased Apoptosis. Pneumologie (12). https://doi.org/10.1055/s-0031-1296099

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