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Carbon nanotube instillation in mice causes sustained pulmonary inflammation and apoptosis of alveolar macrophages

NC Habel, S Hirn, F Tian, O Eickelberg, T Stoeger · Pneumologie · Ausgabe 12/2011

DOI 10.1055/s-0031-1296111

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Autor:innenNC Habel, S Hirn, F Tian, O Eickelberg, T Stoeger
ZeitschriftPneumologie
Ausgabe12/2011
Jahrgang / SeitenNicht angegeben

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Introduction: Inhalation of nanoparticles has been associated with acute and chronic pulmonary inflammation. The underlying pathways however are mostly unknown. Due to their phagocytic activity, alveolar macrophages (AM) are considered to play an important role in triggering the toxicological response to inhaled particles. Results: Here, we show that a single exposure of mice to fibrous carbon nanotubes (CNT) but no…

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NC Habel, S Hirn, F Tian, O Eickelberg, T Stoeger (2011) Carbon nanotube instillation in mice causes sustained pulmonary inflammation and apoptosis of alveolar macrophages. Pneumologie (12). https://doi.org/10.1055/s-0031-1296111

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