CareLit · DOI-Nachweis · Pneumologie
Evaluation of a new proteasome inhibitor for treatment of lung fibrosis
DOI 10.1055/s-0031-1296133
Bibliografische Angaben
Nachweis in CareLit
Autor:innenN Pfister, O Eickelberg, S Meiners
ZeitschriftPneumologie
Ausgabe12/2011
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: So far treatment options in lung fibrosis are very limited and lung transplantation still remains the only therapy in severe cases. Proteasome inhibition has been reported to prevent development of fibrosis in several organs like liver, skin, kidney, heart, or bone marrow. Non-toxic doses of proteasome inhibitors effectively reduce deposition of collagens, expression of MMPs, and TGFß signaling. However,…
Zitieren
Zitierempfehlung
N Pfister, O Eickelberg, S Meiners (2011) Evaluation of a new proteasome inhibitor for treatment of lung fibrosis. Pneumologie (12). https://doi.org/10.1055/s-0031-1296133
Mit CareLit weiterarbeiten