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Role of Surfactant Proteins in the interaction of nanoparticles with the air-blood-barrier

CA Ruge, UF Schäfer, J Kirch, M Schneider, O Cañadas, J Perez-Gil, C Casals, CM Lehr · Pneumologie · Ausgabe 12/2011

DOI 10.1055/s-0031-1296141

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Autor:innenCA Ruge, UF Schäfer, J Kirch, M Schneider, O Cañadas, J Perez-Gil, C Casals, CM Lehr
ZeitschriftPneumologie
Ausgabe12/2011
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Purpose: Pulmonary surfactant (PS) is the first biological matter a nanoparticle (NP) encounters after deposition into the alveolar lumen. This complex mixture of lipids and proteins offers a pool of biomolecules that can undergo bio-nano-interactions. Especially adsorption of the prevailing Surfactant Protein A (SP-A) might lead a NP – protein corona, that probably largely influences further biological effects like…

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Zitierempfehlung

CA Ruge, UF Schäfer, J Kirch, M Schneider, O Cañadas, J Perez-Gil, C Casals, CM Lehr (2011) Role of Surfactant Proteins in the interaction of nanoparticles with the air-blood-barrier. Pneumologie (12). https://doi.org/10.1055/s-0031-1296141

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