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Local delivery of Granulocyte/Macrophage Colony Stimulating Factor protects mice from lethal pneumococcal pneumonia

K Steinwede, R Maus, J Bohling, B Ueberberg, T Welte, UA Maus · Pneumologie · Ausgabe 12/2011

DOI 10.1055/s-0031-1296152

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Autor:innenK Steinwede, R Maus, J Bohling, B Ueberberg, T Welte, UA Maus
ZeitschriftPneumologie
Ausgabe12/2011
Jahrgang / SeitenNicht angegeben

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Introduction: The growth factor granulocyte/macrophage-colony stimulating factor (GM-CSF) has an important role in pulmonary surfactant metabolism and the regulation of antibacterial activities of lung sentinel cells. However, the potential of intra-alveolar GM-CSF to augment lung protective immunity against inhaled bacterial pathogens has not been defined in preclinical infection models. We hypothesized that transi…

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K Steinwede, R Maus, J Bohling, B Ueberberg, T Welte, UA Maus (2011) Local delivery of Granulocyte/Macrophage Colony Stimulating Factor protects mice from lethal pneumococcal pneumonia. Pneumologie (12). https://doi.org/10.1055/s-0031-1296152

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