CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Permeabilization of the Tight Junction: A Perspective for Tissue-Specific Drug Targeting
DOI 10.1055/s-0031-1304769
Bibliografische Angaben
Nachweis in CareLit
Autor:innenSalah Amasheh, Rita Rosenthal, Jörg-Dieter Schulzke, Michael Fromm
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Abstract Epithelial barrier properties are determined by three components, namely transcellular permeability, the paracellular pathway, and locally limited peaks of permeability caused by apoptoses. Whereas transcellular permeability is strongly dependent on polarity or specific substrate recognition by membrane receptors and transport proteins, a promising target for specific permeabilization is the tight junction.…
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Zitierempfehlung
Salah Amasheh, Rita Rosenthal, Jörg-Dieter Schulzke, Michael Fromm (2012) Permeabilization of the Tight Junction: A Perspective for Tissue-Specific Drug Targeting. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0031-1304769
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