CareLit · DOI-Nachweis · Klinische Neurophysiologie
Decreased Dopamine D2/D3-Receptor Binding in the Temporal Lobe and the Bilateral Basal Ganglia in patients with Temporal Lobe Epilepsy
DOI 10.1055/s-0032-1301572
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Nachweis in CareLit
Autor:innenVE Bernedo Paredes, H Schwartz, M Gartenschläger, M Gartenschläger, HG Buchholz, M Breimhorst, M Schreckenberger, KJ Werhahn
ZeitschriftKlinische Neurophysiologie
Ausgabe03/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Dopamine is an endogenous neuromodulator in cortical circuits and basal ganglia. In animal models, it is known to affect seizure threshold and might have a neuroprotective role in temporal lobe epilepsy (TLE).1 In animal models of TLE activation of D1- has a pro- and of D2-receptors (D2R) an anticonvulsant effect. To quantify D2/D3 receptor binding we studied 26 patients with TLE and 18 controls by PET using the hig…
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Zitierempfehlung
VE Bernedo Paredes, H Schwartz, M Gartenschläger, M Gartenschläger, HG Buchholz, M Breimhorst, M Schreckenberger, KJ Werhahn (2012) Decreased Dopamine D2/D3-Receptor Binding in the Temporal Lobe and the Bilateral Basal Ganglia in patients with Temporal Lobe Epilepsy. Klinische Neurophysiologie (03). https://doi.org/10.1055/s-0032-1301572
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