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Induction of LTD-like plasticity by paired associative stimulation is blocked by intracortical inhibition

DT Weise, MC Ridding, R Gentner, JJ Rumpf, J Classen · Klinische Neurophysiologie · Ausgabe 03/2012

DOI 10.1055/s-0032-1301601

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Autor:innenDT Weise, MC Ridding, R Gentner, JJ Rumpf, J Classen
ZeitschriftKlinische Neurophysiologie
Ausgabe03/2012
Jahrgang / SeitenNicht angegeben

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Objective/Aims: Paired associative stimulation (PAS) of the hand motor cortex (M1) may induce depressant effects on corticospinal excitability. It has been likened to the long-term depression of excitatory synapses as studied in vivo animal work. We hypothesized that activation of inhibitory and/or facilitatory interneurons during PAS may modulate LTD-like plasticity. Methods: 60 subjects were examined (20 in every…

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DT Weise, MC Ridding, R Gentner, JJ Rumpf, J Classen (2012) Induction of LTD-like plasticity by paired associative stimulation is blocked by intracortical inhibition. Klinische Neurophysiologie (03). https://doi.org/10.1055/s-0032-1301601

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