CareLit · DOI-Nachweis · Klinische Neurophysiologie
Effects of Lithium on Plasticity in Human Motor Cortex Induced by Paired Associative Stimulation
DOI 10.1055/s-0032-1301607
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Autor:innenH Voytovych, L Krivanekova, U Ziemann
ZeitschriftKlinische Neurophysiologie
Ausgabe03/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Lithium is widely used for the treatment of bipolar disorders. Relatively little is known about the CNS actions of lithium. One mode of action is that lithium inhibits the GSK–3ß kinase, an enzyme that in rat hippocampal slices mediates an interaction between two major forms of synaptic plasticity, i.e. long-term potentiation (LTP) and long-term depression (LTD). Inhibition of GSK–3ß favors LTP over LTD.…
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Zitierempfehlung
H Voytovych, L Krivanekova, U Ziemann (2012) Effects of Lithium on Plasticity in Human Motor Cortex Induced by Paired Associative Stimulation. Klinische Neurophysiologie (03). https://doi.org/10.1055/s-0032-1301607
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