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Cellular Stress and Homeostatic Mechanisms Involved in Reduced Innate Immunity in Cystic Fibrosis Cell Lines

S Chillappagari, G Sarode, H Shah, MO Henke · Pneumologie · Ausgabe 02/2012

DOI 10.1055/s-0032-1302603

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Autor:innenS Chillappagari, G Sarode, H Shah, MO Henke
ZeitschriftPneumologie
Ausgabe02/2012
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Cystic fibrosis (CF) is commonly associated with bacterial infection of the airways usually with P. aeruginosa and S. aureus. The chronic endobronchial inflammation due to persistent bacterial infection leads to progressive lung disease and is the main cause of mortality and morbidity in CF. These observations suggest a modified immune response in CF. In response, toll like receptors (TLR) act as sensors for the bac…

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Zitierempfehlung

S Chillappagari, G Sarode, H Shah, MO Henke (2012) Cellular Stress and Homeostatic Mechanisms Involved in Reduced Innate Immunity in Cystic Fibrosis Cell Lines. Pneumologie (02). https://doi.org/10.1055/s-0032-1302603

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