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A randomized phase 2 study of pemetrexed vs. pemetrexed+erlotinib in second-line treatment for locally advanced or metastatic, non-squamous NSCLC

J von Pawel, Z Papai-Szekely, N Vinolas, C Sederholm, M Klima, D Desaiah, M Leschinger, C Dittrich · Pneumologie · Ausgabe 02/2012

DOI 10.1055/s-0032-1302878

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Autor:innenJ von Pawel, Z Papai-Szekely, N Vinolas, C Sederholm, M Klima, D Desaiah, M Leschinger, C Dittrich
ZeitschriftPneumologie
Ausgabe02/2012
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: PEM and ERL have been approved as second-line monotherapy for locally advanced or metastatic NSCLC. The combination of PEM + ERL showed synergistic activity in preclinical studies. This multicenter, randomized, open-label study assessed the efficacy and safety of PEM + ERL vs. PEM. Methods: Patients (pts) with NSQ NSCLC who have failed one prior platinum-based chemotherapy regimen for advanced or metasta…

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Zitierempfehlung

J von Pawel, Z Papai-Szekely, N Vinolas, C Sederholm, M Klima, D Desaiah, M Leschinger, C Dittrich (2012) A randomized phase 2 study of pemetrexed vs. pemetrexed+erlotinib in second-line treatment for locally advanced or metastatic, non-squamous NSCLC. Pneumologie (02). https://doi.org/10.1055/s-0032-1302878

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