CareLit · DOI-Nachweis · Klinische Pädiatrie
TRAIL targets cell cycle arrested tumor cells
DOI 10.1055/s-0032-1310476
Bibliografische Angaben
Nachweis in CareLit
Autor:innenF Wachter, M Grunert, I Jeremias, H Ehrhardt
ZeitschriftKlinische Pädiatrie
Ausgabe04/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Cell cycle arrested and resting tumor cells represent a major challenge for anti-tumor therapy as they display enhanced resistance against chemotherapy and induce disease relapse. Materials and Methods: Cell cycle arrest was induced by cytotoxic drugs, irradiation or knockdown of specific cyclins both in tumor cell lines and in cells derived from leukemia patients. Results: Against all expectations, ce…
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Zitierempfehlung
F Wachter, M Grunert, I Jeremias, H Ehrhardt (2012) TRAIL targets cell cycle arrested tumor cells. Klinische Pädiatrie (04). https://doi.org/10.1055/s-0032-1310476
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