CareLit · DOI-Nachweis · Klinische Pädiatrie
Side effects of tyrosine kinase inhibitors (TKIs) on bone remodelling
DOI 10.1055/s-0032-1310478
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Nachweis in CareLit
Autor:innenJT Tauer, A Ulmer, LC Hofbauer, M Suttorp
ZeitschriftKlinische Pädiatrie
Ausgabe04/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Patients with CML on TKI treatment may show altered bone metabolism. We investigated the influence of the TKIs imatinib (IMA), Dasatinib (DASA), and Bosutinib (BOSU) on the growing skeleton in juvenile rats. Methods: 4 weeks-old rats were chronically exposed to TKIs over a 10 week period. At fixed time points animals were sacrificed to analyze the following parameters: bone length, bone mineral density (…
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Zitierempfehlung
JT Tauer, A Ulmer, LC Hofbauer, M Suttorp (2012) Side effects of tyrosine kinase inhibitors (TKIs) on bone remodelling. Klinische Pädiatrie (04). https://doi.org/10.1055/s-0032-1310478
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