CareLit · DOI-Nachweis · Klinische Pädiatrie
Application of genomic breakpoints as molecular markers in pediatric leukemia and sarcoma
DOI 10.1055/s-0032-1310480
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Krumbholz, H von Goessel, M Karl, M Berger, M Metzler
ZeitschriftKlinische Pädiatrie
Ausgabe04/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Chromosomal translocations and the resultant fusion genes are recurrent tumor-specific markers of a large spectrum of pediatric tumors, particularly leukemia and sarcoma. The use of DNA fusion sequences as genomic minimal residual disease markers is often hampered by the extended size of breakpoint cluster regions, difficult to cover by conventional PCR applications. We developed and optimized nested multiplex long-…
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Zitierempfehlung
M Krumbholz, H von Goessel, M Karl, M Berger, M Metzler (2012) Application of genomic breakpoints as molecular markers in pediatric leukemia and sarcoma. Klinische Pädiatrie (04). https://doi.org/10.1055/s-0032-1310480
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