CareLit · DOI-Nachweis · Klinische Pädiatrie
Genetic aberrations involved in glucocorticoid-mediated response of ETV6/RUNX1-positive leukemia
DOI 10.1055/s-0032-1310486
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Bastelberger, R Grausenburger, C Eckert, M Stanulla, R Panzer-Grümayer
ZeitschriftKlinische Pädiatrie
Ausgabe04/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The t(12;21) is the most frequent chromosomal translocation in childhood acute lymphoblastic leukemia (ALL), generating the ETV6/RUNX1 (E/R) fusion gene, and generally associated with excellent initial treatment response. Relapses, however, occurring in up to 20% of cases, are often associated with drug resistance and dismal outcome. We recently reported on the particularly high frequency of genomic aberrations in g…
Zitieren
Zitierempfehlung
S Bastelberger, R Grausenburger, C Eckert, M Stanulla, R Panzer-Grümayer (2012) Genetic aberrations involved in glucocorticoid-mediated response of ETV6/RUNX1-positive leukemia. Klinische Pädiatrie (04). https://doi.org/10.1055/s-0032-1310486
Mit CareLit weiterarbeiten