CareLit · DOI-Nachweis · Klinische Pädiatrie
Haematopoietic Stem Cell Survival and Transplantation Efficacy is Limited by the BH3-only Proteins Bim and Bmf
DOI 10.1055/s-0032-1310488
Bibliografische Angaben
Nachweis in CareLit
Autor:innenD Bertele, V Labi, C Woess, G Grothe, S Schwemmers, HL Pahl, S Geley, M Kunze, CM Niemeyer, A Villunger, M Erlacher
ZeitschriftKlinische Pädiatrie
Ausgabe04/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Cell death occurring in haematopoietic stem cells (HSC) is critically involved in limiting successful stem cell transfer. It is known that HSC homeostasis is regulated by anti-apoptotic Bcl-2 family members, but little is known about the role of their antagonists, the “BH3-only” proteins. We determined the consequences of BH3-only protein depletion on HSC survival in vitro and in vivo. Thereby, we identified two BH3…
Zitieren
Zitierempfehlung
D Bertele, V Labi, C Woess, G Grothe, S Schwemmers, HL Pahl, S Geley, M Kunze, CM Niemeyer, A Villunger, M Erlacher (2012) Haematopoietic Stem Cell Survival and Transplantation Efficacy is Limited by the BH3-only Proteins Bim and Bmf. Klinische Pädiatrie (04). https://doi.org/10.1055/s-0032-1310488
Mit CareLit weiterarbeiten