CareLit · DOI-Nachweis · Klinische Pädiatrie
Molecular analysis of MTSS1 in gliomas
DOI 10.1055/s-0032-1310491
Bibliografische Angaben
Nachweis in CareLit
Autor:innenD Luxen, M Gessi, LJ Isselstein, T Müller, D Freihoff, J Freihoff, A Becker, M Simon, T Pietsch, A Waha
ZeitschriftKlinische Pädiatrie
Ausgabe04/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
In a genome-wide methylation analysis, the metastasis suppressor-1 (MTSS1) gene was identified as a novel gene hypermethylated in gliomas. MTSS1 interacts with actin filaments and promotes Gli dependent transcriptional regulation. Here we investigate MTSS1 methylation, allelic loss and expression in 63 gliomas and 6 glioma cell lines by pyrosequencing, realtime RT-PCR and IHC. MTSS1 was overexpressed in glioma cell…
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Zitierempfehlung
D Luxen, M Gessi, LJ Isselstein, T Müller, D Freihoff, J Freihoff, A Becker, M Simon, T Pietsch, A Waha (2012) Molecular analysis of MTSS1 in gliomas. Klinische Pädiatrie (04). https://doi.org/10.1055/s-0032-1310491
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