CareLit · DOI-Nachweis · Klinische Pädiatrie
Analysis of chromosome 1q gain as genetic marker for risk stratification of pediatric ependymoma patients by multiplex ligation-dependent probe amplification (MLPA)
DOI 10.1055/s-0032-1310497
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Nachweis in CareLit
Autor:innenN Velez-Char, E Dörner, A zur Mühlen, AO von Beuren, S Rutkowski, T Pietsch
ZeitschriftKlinische Pädiatrie
Ausgabe04/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: In retrospective series of patients suffering ependymoma, gain of material of chromosome arm 1q was identified to predict worse outcome. So far, this marker was mainly assessed by FISH analysis. Methods & Results: To validate this marker in a defined patient cohort, we analysed chromosome 1q in 138 consecutive cases enrolled into the HIT2000 trial in which formalin-fixed, paraffin embedded material was…
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Zitierempfehlung
N Velez-Char, E Dörner, A zur Mühlen, AO von Beuren, S Rutkowski, T Pietsch (2012) Analysis of chromosome 1q gain as genetic marker for risk stratification of pediatric ependymoma patients by multiplex ligation-dependent probe amplification (MLPA). Klinische Pädiatrie (04). https://doi.org/10.1055/s-0032-1310497
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