CareLit · DOI-Nachweis · Klinische Pädiatrie
Stress pathways controlling HNSCC dormancy are differenzially regulated in pediatric ALL cell lines
DOI 10.1055/s-0032-1310505
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Nachweis in CareLit
Autor:innenDM Schewe
ZeitschriftKlinische Pädiatrie
Ausgabe04/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: In pediatric ALL, achieving complete remission shortly after therapy initiation isprognostic, but little is known on dormancy of leukemic cells surviving chemotherapy in the bone marrow (BM) niche. InHNSCC, dormancy is maintained by MAPK-dependent regulation of stress pathways in the ER. Mediators of ER-stress orchestrate a cellular response characterized by growth arrest and survival upon chemotherape…
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Zitierempfehlung
DM Schewe (2012) Stress pathways controlling HNSCC dormancy are differenzially regulated in pediatric ALL cell lines. Klinische Pädiatrie (04). https://doi.org/10.1055/s-0032-1310505
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