CareLit · DOI-Nachweis · Klinische Pädiatrie
The protein-protein interaction network within human AF4 and AF4-MLL protein complexes
DOI 10.1055/s-0032-1310508
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Nachweis in CareLit
Autor:innenT Rössler, B Scholz, T Dingermann, R Marschalek
ZeitschriftKlinische Pädiatrie
Ausgabe04/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
We have recently established the composition and function of the human AF4 and AF4-MLL fusion protein complex (Benedikt et al., 2011). The AF4 complex is responsible for transcriptional elongation, while the AF4-MLL complex is causing ectopic transcription, ectopic histone signatures and was shown to induce proB ALL in a mouse model. The composition of both complexes has been eludidated by using affinity-purificatio…
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Zitierempfehlung
T Rössler, B Scholz, T Dingermann, R Marschalek (2012) The protein-protein interaction network within human AF4 and AF4-MLL protein complexes. Klinische Pädiatrie (04). https://doi.org/10.1055/s-0032-1310508
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