CareLit · DOI-Nachweis · Klinische Pädiatrie
mRNA and Protein Expression Levels of Secretory Leukocyte Protease Inhibitor (SLPI) are Severely Reduced in Patients with Severe Congenital Neutropenia (CN)
DOI 10.1055/s-0032-1310514
Bibliografische Angaben
Nachweis in CareLit
Autor:innenO Klimenkova, W Ellerbeck, A Gigina, J Skokowa, K Welte
ZeitschriftKlinische Pädiatrie
Ausgabe04/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Secretory Leukocyte Protease Inhibitor (SLPI) is a cationic serine protease inhibitor with antiprotease, primarily anti-NeutrophilELastase (NE), activities. The molecular interaction and the balance between NE and SLPI is tightly regulated. We identified severe diminished levels of SLPI mRNA in myeloid cells and in plasma of severe congenital neutropeniapatients (CN), as compared to cyclic neutropeniapatients (CyN)…
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Zitierempfehlung
O Klimenkova, W Ellerbeck, A Gigina, J Skokowa, K Welte (2012) mRNA and Protein Expression Levels of Secretory Leukocyte Protease Inhibitor (SLPI) are Severely Reduced in Patients with Severe Congenital Neutropenia (CN). Klinische Pädiatrie (04). https://doi.org/10.1055/s-0032-1310514
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