CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Contribution of Keratin-18 on steatohepatitis and liver cancer
DOI 10.1055/s-0032-1313844
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Nachweis in CareLit
Autor:innenK Bettermann, AK Mehta, E Lederer, C Diwoky, A Thüringer, H Müller, VS Mahajan, C Stumptner, T Kolbe, TM Magin, H Denk, C Lackner, K Zatloukal, J Haybaeck
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Steatohepatitis (SH) is morphologically characterized by steatosis, hepatocyte ballooning and cytoplasmic protein aggregates termed Mallory-Denk bodies (MDBs). SH arises in about 20% of alcoholics and is tightly associated with obese type II diabetics. MDBs are generally composed of misfolded keratin (K) 8, 18 and in part p62 and ubiquitin. It is well established that Keratin aggregates are critical for…
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Zitierempfehlung
K Bettermann, AK Mehta, E Lederer, C Diwoky, A Thüringer, H Müller, VS Mahajan, C Stumptner, T Kolbe, TM Magin, H Denk, C Lackner, K Zatloukal, J Haybaeck (2012) Contribution of Keratin-18 on steatohepatitis and liver cancer. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0032-1313844
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