CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
A microdeletion within a QTL hotspot on distal mouse chromosome 1 disrupts the Ifi202b gene and modulates metabolic and neuronal phenotypes
DOI 10.1055/s-0032-1314516
Bibliografische Angaben
Nachweis in CareLit
Autor:innenH Vogel, T Kanzleiter, S Scherneck, V Benz, R Kluge, M Blüher, D Montag, HG Joost, A Schürmann
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objectives: The New Zealand Obese (NZO) mouse develops a polygenic disease pattern of obesity, insulin resistance, and dyslipoproteinemia resembling the human metabolic syndrome. By positional cloning we have recently discovered two genes (Tbc1d1, Zfp69) to participate in the development of the disease. In an outcross population of NZO and lean C57BL/6 (B6) mice we identified a major obesity QTL on distal chromosome…
Zitieren
Zitierempfehlung
H Vogel, T Kanzleiter, S Scherneck, V Benz, R Kluge, M Blüher, D Montag, HG Joost, A Schürmann (2012) A microdeletion within a QTL hotspot on distal mouse chromosome 1 disrupts the Ifi202b gene and modulates metabolic and neuronal phenotypes. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0032-1314516
Mit CareLit weiterarbeiten