CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Sfrp5 serum concentration is associated with measures of glucose homeostasis and insulin sensitivity in human obesity
DOI 10.1055/s-0032-1314529
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Autor:innenG Flehmig, M Fasshauer, N Klöting, MR Schön, M Stumvoll, M Blüher
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: Secreted frizzled-related protein-5 (SFRP5) has been identified to antagonize Wnt signalling as a central pathway of adipogenesis which is related to metabolic disorders. Mice with a disruption of SFRP5 have elevated fasting glucose and insulin levels upon high fat and high-sucrose diet. SFRP5 expression in mature adipocytes correlates with increasing adiposity. Materials and methods: We investi…
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Zitierempfehlung
G Flehmig, M Fasshauer, N Klöting, MR Schön, M Stumvoll, M Blüher (2012) Sfrp5 serum concentration is associated with measures of glucose homeostasis and insulin sensitivity in human obesity. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0032-1314529
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