CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
S100A8/A9 aggravates post-ischemic heart failure through activation of RAGE-dependent NF-kB signaling
DOI 10.1055/s-0032-1314767
Bibliografische Angaben
Nachweis in CareLit
Autor:innenC Volz, AR Wienbrandt, HA Katus, F Lasitschka, M Andrassy
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe08/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The extracellular heterodimeric protein S100A8/A9 activates the innate immune system through activation of the receptor of advanced glycation endproducts (RAGE) and Toll-like receptors. As activation of RAGE has recently been associated with sustained myocardial inflammation and heart failure (HF) we studied the role of S100A8/A9 in the development of post-ischemic HF. Hypoxia led to sustained induction of S100A8/A9…
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Zitierempfehlung
C Volz, AR Wienbrandt, HA Katus, F Lasitschka, M Andrassy (2012) S100A8/A9 aggravates post-ischemic heart failure through activation of RAGE-dependent NF-kB signaling. Diabetologie und Stoffwechsel (08). https://doi.org/10.1055/s-0032-1314767
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