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Influenza-virus infection impacts on alveolar edema clearance: role of virus- and host factors in regulation of alveolar epithelial cell ENaC and Na,K-ATPase expression

C Becker, NM Gabrielli, S Budinger, W Seeger, J Lohmeyer, R Morty, S Herold · Pneumologie · Ausgabe 05/2012

DOI 10.1055/s-0032-1315459

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Autor:innenC Becker, NM Gabrielli, S Budinger, W Seeger, J Lohmeyer, R Morty, S Herold
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben

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Influenza A viruses (IV) can cause primary viral pneumonia in humans resulting in acute lung injury (ALI/ARDS) with fatal outcome. One of the hallmarks of IV-induced ALI is the accumulation of edema fluid in the alveolar compartment, which under normal conditions is cleared along a sodium gradient established by basolateral Na,K-ATPase and the apical epithelial sodium channel (ENaC). IV-infection was found to be ass…

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C Becker, NM Gabrielli, S Budinger, W Seeger, J Lohmeyer, R Morty, S Herold (2012) Influenza-virus infection impacts on alveolar edema clearance: role of virus- and host factors in regulation of alveolar epithelial cell ENaC and Na,K-ATPase expression. Pneumologie (05). https://doi.org/10.1055/s-0032-1315459

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