CareLit · DOI-Nachweis · Pneumologie
Role of Interleukin-1 (IL-1)-receptor-associated kinase 1 (IRAK-1) in pulmonary inflammation
DOI 10.1055/s-0032-1315460
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Nachweis in CareLit
Autor:innenJ Visic, M Cabanski, G Hansen
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: A crucial transducer of many Toll-like receptor (TLR) and IL-1 signalling pathways is IRAK-1. IRAK-1 deficient macrophages and fibroblasts show impaired responses to TLR ligands like lipopolysaccharide (LPS). However, the role of IRAK-1 in pulmonary inflammation has not been investigated yet. Methods: IRAK-1 knockout (KO) and WT mice were challenged for 9h or 24h intranasally with either high or low dose…
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Zitierempfehlung
J Visic, M Cabanski, G Hansen (2012) Role of Interleukin-1 (IL-1)-receptor-associated kinase 1 (IRAK-1) in pulmonary inflammation. Pneumologie (05). https://doi.org/10.1055/s-0032-1315460
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