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Ubiquitination-driven down-regulation of the cell adhesion molecule Na,K-ATPase β-subunit by hypercapnia in alveolar epithelial cells

NM Gabrielli, B Grzesik, CU Vohwinkel, LA Dada, W Seeger, JI Sznajder, I Vadász · Pneumologie · Ausgabe 05/2012

DOI 10.1055/s-0032-1315461

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Autor:innenNM Gabrielli, B Grzesik, CU Vohwinkel, LA Dada, W Seeger, JI Sznajder, I Vadász
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Acute lung injury (ALI) is associated with alveolo-capillary barrier dysfunction leading to impaired gas exchange and thus elevated CO2 levels (hypercapnia). In addition to the well-studied role of the α-subunit of the Na,K-ATPase in alveolar edema fluid clearance during ALI, the Na,K-ATPase β-subunit located at the sites of cell-cell junction acts as a cell adhesion molecule and therefore might be an important play…

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Zitierempfehlung

NM Gabrielli, B Grzesik, CU Vohwinkel, LA Dada, W Seeger, JI Sznajder, I Vadász (2012) Ubiquitination-driven down-regulation of the cell adhesion molecule Na,K-ATPase β-subunit by hypercapnia in alveolar epithelial cells. Pneumologie (05). https://doi.org/10.1055/s-0032-1315461

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