CareLit · DOI-Nachweis · Pneumologie
Improved outcome of FAT mice in a model of acute lung injury in spite of increased spleenic lymphocytes apoptosis
DOI 10.1055/s-0032-1315464
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Ott, M Krebs, C Wolff, A Kiessling, A Buchbinder, J Grabitzki, M Hecker, J Roth, W Seeger, K Mayer
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
ALI and sepsis are still major causes of mortality in intensive care units. After the first hyperinflammatory stage an immunparalyis characterized by apoptosis of spleenic lymphocytes (SL) ensues. Lipid mediators derived from n-6 fatty acids (FA) control inflammation and apoptosis. N-3 FA derived mediators display reduced inflammatory potency. FAT mice are capable of synthesizing n-3 FA from n-6 FA. We induced ALI i…
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Zitierempfehlung
J Ott, M Krebs, C Wolff, A Kiessling, A Buchbinder, J Grabitzki, M Hecker, J Roth, W Seeger, K Mayer (2012) Improved outcome of FAT mice in a model of acute lung injury in spite of increased spleenic lymphocytes apoptosis. Pneumologie (05). https://doi.org/10.1055/s-0032-1315464
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