CareLit · DOI-Nachweis · Pneumologie
Transforming growth factor-β inhibits alveolar epithelial protein transport by glycogen synthase kinase 3-β-mediated downregulation of megalin
DOI 10.1055/s-0032-1315465
Bibliografische Angaben
Nachweis in CareLit
Autor:innenCU Vohwinkel, Y Buchäckert, S Rummel, RE Morty, W Seeger, I Vadász
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
A hallmark of acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is the accumulation of protein-rich edema fluid in the distal airspaces removal of which is critical for patient survival. We have previously shown that albumin transport across the alveolar epithelial barrier is an active process mediated by megalin. Here we set out to identify the mechanisms that may impair megalin function upon ALI/ARD…
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Zitierempfehlung
CU Vohwinkel, Y Buchäckert, S Rummel, RE Morty, W Seeger, I Vadász (2012) Transforming growth factor-β inhibits alveolar epithelial protein transport by glycogen synthase kinase 3-β-mediated downregulation of megalin. Pneumologie (05). https://doi.org/10.1055/s-0032-1315465
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