CareLit · DOI-Nachweis · Pneumologie
LMP7 Subunit Deficiency of the Immunoproteasome Leads to reduced Th2 Response in OVA/Alum Acute Asthma
DOI 10.1055/s-0032-1315468
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Volkov, S Hagner-Benes, S Löser, H Raifer, A Hellhund, S Alnahas, A Visekruna, H Garn, M Lohoff, H Renz, U Steinhoff
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
LMP7 subunit of the immunoproteasome has been shown to play an important role in Th1/Th17 driven models of colitis and arthritis. However, nothing is known about LMP7 function in Th2 dependent diseases. To study the role of LMP7 in Th2 driven pathology, experimental allergic asthma was selected as a model of the medically relevant disease. We used WT and LMP7-/- knockout (KO) mice of C57BL/6N background for the indu…
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Zitierempfehlung
A Volkov, S Hagner-Benes, S Löser, H Raifer, A Hellhund, S Alnahas, A Visekruna, H Garn, M Lohoff, H Renz, U Steinhoff (2012) LMP7 Subunit Deficiency of the Immunoproteasome Leads to reduced Th2 Response in OVA/Alum Acute Asthma. Pneumologie (05). https://doi.org/10.1055/s-0032-1315468
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