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ICOS mediates the generation and function of CD4+CD25+Foxp3+ regulatory T cells conveying respiratory tolerance

M Busse, M Krech, A Meyer-Balburg, G Hansen · Pneumologie · Ausgabe 05/2012

DOI 10.1055/s-0032-1315469

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Autor:innenM Busse, M Krech, A Meyer-Balburg, G Hansen
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben

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Background: Costimulatory molecules like ICOS are important for the activation and differentiation of T lymphocytes upon allergen contact and thereby strongly affect the decision between the maintaining of tolerance or development of allergic immune response. Methods: Three independent approaches were used to investigate the role of ICOS-mediated costimulation in the development of respiratory tolerance. First, WT m…

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M Busse, M Krech, A Meyer-Balburg, G Hansen (2012) ICOS mediates the generation and function of CD4+CD25+Foxp3+ regulatory T cells conveying respiratory tolerance. Pneumologie (05). https://doi.org/10.1055/s-0032-1315469

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