CareLit · DOI-Nachweis · Pneumologie
Mechanism of bronchopulmonary C-fiber hyperexcitability in allergic asthma: Loss of TRPV1 inhibition by GDNF downregulation?
DOI 10.1055/s-0032-1315476
Bibliografische Angaben
Nachweis in CareLit
Autor:innenR Nandigama, A Weske, S Wiegand, W Kummer, C Nassenstein
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Sensory C-fibers activation contributes to several symptoms in allergic asthma, e.g. cough, dyspnea and bronchoconstriction. Many environmental irritants that cause asthma attacks (including ozone, cold air, cigarette smoke) are ligands of the transient receptor potential (TRP) channel family members that includes TRPV1. Therefore, it has been speculated that dysfunction of TRP channels is responsible for the enhanc…
Zitieren
Zitierempfehlung
R Nandigama, A Weske, S Wiegand, W Kummer, C Nassenstein (2012) Mechanism of bronchopulmonary C-fiber hyperexcitability in allergic asthma: Loss of TRPV1 inhibition by GDNF downregulation?. Pneumologie (05). https://doi.org/10.1055/s-0032-1315476
Mit CareLit weiterarbeiten