CareLit · DOI-Nachweis · Pneumologie
Nontypeable Haemophilus influenzae activates the NLRP3 inflammasome and leads to Caspase-1 dependent secretion of IL-1beta – a possible pathway of exacerbations in COPD
DOI 10.1055/s-0032-1315489
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Rohmann, J Rotta detto Loria, D Droemann, J Rupp, T Goldmann, K Dalhoff
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The inflammasome is a cytosolic protein complex important for early inflammatory responses of the innate immunity. Inflammasome activation has been described for several types of infection, and our data indicate that also nontypeable Haemophilus influenzae (NTHi) induces the assembly of the inflammasome components. The inflammasome consists of NOD-like receptors such as NLRP3, the adaptor protein ASC and Caspase-1 w…
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Zitierempfehlung
K Rohmann, J Rotta detto Loria, D Droemann, J Rupp, T Goldmann, K Dalhoff (2012) Nontypeable Haemophilus influenzae activates the NLRP3 inflammasome and leads to Caspase-1 dependent secretion of IL-1beta – a possible pathway of exacerbations in COPD. Pneumologie (05). https://doi.org/10.1055/s-0032-1315489
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