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Diverging Proliferative Behavior of Alveolar Epithelial Cells in Progressive Elastase-Induced Emphysema

A Bohla, K Kohse, J Schwarz, G John, OV Amarie, O Eickelberg, AÖ Yildirim · Pneumologie · Ausgabe 05/2012

DOI 10.1055/s-0032-1315495

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Autor:innenA Bohla, K Kohse, J Schwarz, G John, OV Amarie, O Eickelberg, AÖ Yildirim
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben

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Rationale: Development of emphysema is typical for chronic obstructive pulmonary disease (COPD). We already showed that a single application of porcine pancreatic elastase (PPE) causes a severe progressing emphysema-like phenotype in C57BL/6 mice. Emphysema formation is apparently not completed after PPE application, so we aimed to identify possible key mechanisms that drive this process even at late time points. Me…

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Zitierempfehlung

A Bohla, K Kohse, J Schwarz, G John, OV Amarie, O Eickelberg, AÖ Yildirim (2012) Diverging Proliferative Behavior of Alveolar Epithelial Cells in Progressive Elastase-Induced Emphysema. Pneumologie (05). https://doi.org/10.1055/s-0032-1315495

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