CareLit · DOI-Nachweis · Pneumologie
Elastase inhibition is not a requirement for the anti-inflammatory effects of Alpha-1 Antitrypsin: studies in neutrophil models
DOI 10.1055/s-0032-1315496
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Nachweis in CareLit
Autor:innenE Frenzel, N Aggarwal, S Wrenger, T Welte, S Janciauskiene
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
As an acute phase protein, alpha-antitrypsin (AAT) is thought to play an important role in limiting host tissue injury by proteases released from activated myeloid cells, specifically neutrophil elastase (NE). The clinical importance of AAT is highlighted in individuals with inherited deficiency in circulating AAT who have an increased susceptibility to early onset pulmonary emphysema, chronic bronchitis, bronchiect…
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Zitierempfehlung
E Frenzel, N Aggarwal, S Wrenger, T Welte, S Janciauskiene (2012) Elastase inhibition is not a requirement for the anti-inflammatory effects of Alpha-1 Antitrypsin: studies in neutrophil models. Pneumologie (05). https://doi.org/10.1055/s-0032-1315496
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