CareLit · DOI-Nachweis · Pneumologie
Stimulation of Soluble Guanylate Cyclase by Riociguat prevents Tobacco smoke-induced Pulmonary Hypertension in mice
DOI 10.1055/s-0032-1315498
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Nachweis in CareLit
Autor:innenA Pichl, N Parajuli, M Seimetz, JP Stasch, R Frey, RT Schermuly, W Seeger, F Grimminger, HA Ghofrani, N Weissmann
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Rationale: Chronic obstructive pulmonary disease (COPD) is a severe cause of death worldwide. An estimated portion of 30–70% of Chronic Obstructive Pulmonary Disease (COPD) patients also suffer from pulmonary hypertension (PH). Previous studies in PH show that stimulation of soluble guanylate cyclase (sGC) with riociguat partially reversed PH. In further studies we demonstrated that the sGC stimulator riociguat prev…
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Zitierempfehlung
A Pichl, N Parajuli, M Seimetz, JP Stasch, R Frey, RT Schermuly, W Seeger, F Grimminger, HA Ghofrani, N Weissmann (2012) Stimulation of Soluble Guanylate Cyclase by Riociguat prevents Tobacco smoke-induced Pulmonary Hypertension in mice. Pneumologie (05). https://doi.org/10.1055/s-0032-1315498
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