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Iron induced HIF destabilization and altered Cellular Homeostatic Mechanisms in Cystic Fibrosis Cell Lines

S Chillappagari, S Venkatesan, MO Henke · Pneumologie · Ausgabe 05/2012

DOI 10.1055/s-0032-1315508

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Autor:innenS Chillappagari, S Venkatesan, MO Henke
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben

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Introduction: Cystic fibrosis (CF) is commonly associated with bacterial infection of the airways usually with P. aeruginosa and S. aureus. The chronic endobronchial inflammation due to persistent bacterial infection leads to progressive lung disease and is the main cause of mortality and morbidity in CF. Toll like receptors (TLR) act as sensors for the bacterial infections through conserved pathogen assisted molecu…

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S Chillappagari, S Venkatesan, MO Henke (2012) Iron induced HIF destabilization and altered Cellular Homeostatic Mechanisms in Cystic Fibrosis Cell Lines. Pneumologie (05). https://doi.org/10.1055/s-0032-1315508

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