CareLit · DOI-Nachweis · Pneumologie
Regulation and localization of the Telomerase- and the Shelterin-telosom-complex in sporadic Idiopathic Pulmonary Fibrosis
DOI 10.1055/s-0032-1315512
Bibliografische Angaben
Nachweis in CareLit
Autor:innenU Tenekeci, W Klepetko, L Fink, W Seeger, A Guenther, M Korfei
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Idiopathic pulmonary fibrosis (IPF) is an adult-onset, lethal, scarring lung disease of unknown etiology. Reports linking telomerase mutations to familial IPF suggest that reduced telomerase activity and defective telomere length maintenance are key factors in disease pathogenesis. Accelerated telomere shortening is also observed in sporadic IPF in the absence of gene mutations. We therefore aimed to a…
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Zitierempfehlung
U Tenekeci, W Klepetko, L Fink, W Seeger, A Guenther, M Korfei (2012) Regulation and localization of the Telomerase- and the Shelterin-telosom-complex in sporadic Idiopathic Pulmonary Fibrosis. Pneumologie (05). https://doi.org/10.1055/s-0032-1315512
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