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Role of autophagy in the development of amiodarone induced pulmonary fibrosis

P Mahavadi, C Ruppert, I Henneke, L Knudsen, R Chambers, M Ochs, M Korfei, W Seeger, A Guenther · Pneumologie · Ausgabe 05/2012

DOI 10.1055/s-0032-1315519

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Autor:innenP Mahavadi, C Ruppert, I Henneke, L Knudsen, R Chambers, M Ochs, M Korfei, W Seeger, A Guenther
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben

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Introduction: Amiodarone (AD) is a well known anti arrhythmic drug, but is limited by its potential side effects. Severe pulmonary toxicity is reported in patients receiving amiodarone, with the most common histological finding being chronic interstitial pneumonia. Apoptosis of alveolar epithelial cells type II (AECII) was reported in a rat model of amiodarone induced pulmonary toxicity. However, the underlying mole…

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Zitierempfehlung

P Mahavadi, C Ruppert, I Henneke, L Knudsen, R Chambers, M Ochs, M Korfei, W Seeger, A Guenther (2012) Role of autophagy in the development of amiodarone induced pulmonary fibrosis. Pneumologie (05). https://doi.org/10.1055/s-0032-1315519

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