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The role of Forkhead Box O 3a (FoxO3a) Transcription Factors in the Pathogenesis of Pulmonary Fibrosis

HM Al-Tamari, M Eschenhagen, A Schmall, R Savai, HA Ghofrani, F Grimminger, W Seeger, RT Schermuly, SS Pullamsetti · Pneumologie · Ausgabe 05/2012

DOI 10.1055/s-0032-1315520

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Autor:innenHM Al-Tamari, M Eschenhagen, A Schmall, R Savai, HA Ghofrani, F Grimminger, W Seeger, RT Schermuly, SS Pullamsetti
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Idiopathic Pulmonary Fibrosis (IPF) is a progressive and fatal interstitial pulmonary disease with no proven drug therapy and still unclear signaling mechanisms. Forkhead box O-3a (FoxO3a) transcription factor plays a major role in regulation of cell proliferation and migration. The objectives of this study are to examine how the pro-fibrotic mediators and growth factors regulate FoxO3a protein in primary human lung…

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Zitierempfehlung

HM Al-Tamari, M Eschenhagen, A Schmall, R Savai, HA Ghofrani, F Grimminger, W Seeger, RT Schermuly, SS Pullamsetti (2012) The role of Forkhead Box O 3a (FoxO3a) Transcription Factors in the Pathogenesis of Pulmonary Fibrosis. Pneumologie (05). https://doi.org/10.1055/s-0032-1315520

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