CareLit · DOI-Nachweis · Pneumologie
Regulation of K-Ras-induced signal transduction by Galectin-3 and Galectin-8 in adenocarcioma cell lines of lung and pancreas
DOI 10.1055/s-0032-1315524
Bibliografische Angaben
Nachweis in CareLit
Autor:innenSJ Barnard, S Chakraborty, A Menke, K Giehl
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Activating point mutations in codon 12 or 13 of the monomeric GTPase K-Ras are prominent mutations in adenocarcinoma of the lung and the pancreas. Deregulated activation of K-Ras results in an aberrant activation of downstream effector pathways, which are involved in the regulation of cell proliferation, apoptosis, differentiation and cell migration. Mutations in Ras, which constitutively activate the protein, promo…
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Zitierempfehlung
SJ Barnard, S Chakraborty, A Menke, K Giehl (2012) Regulation of K-Ras-induced signal transduction by Galectin-3 and Galectin-8 in adenocarcioma cell lines of lung and pancreas. Pneumologie (05). https://doi.org/10.1055/s-0032-1315524
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