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A potential role of high mobility group box-1 (HGMB1) in inflammatory vascular remodelling

H Xu, D Zabini, A Olschewski, G Kwapiszewska, LM Marsh · Pneumologie · Ausgabe 05/2012

DOI 10.1055/s-0032-1315536

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Autor:innenH Xu, D Zabini, A Olschewski, G Kwapiszewska, LM Marsh
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Pulmonary hypertension (PH) is a life threatening disease characterised by a progressive remodelling of the pulmonary arteries. Recently, inflammatory processes have been implicated in the development and progression of PH. High mobility group box-1 (HGMB1) is a nuclear protein that acts to stabilise nucleosome formation and regulates transcription. Extracellularly, HGMB1 has an important role in mediating the infla…

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Zitierempfehlung

H Xu, D Zabini, A Olschewski, G Kwapiszewska, LM Marsh (2012) A potential role of high mobility group box-1 (HGMB1) in inflammatory vascular remodelling. Pneumologie (05). https://doi.org/10.1055/s-0032-1315536

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