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Function of NADPH oxidase 1 in pulmonary arterial smooth muscle cells from monocrotaline-induced pulmonary hypertension

F Veit, B Egemnazarov, M Roth, D Kosanovic, O Pak, HA Ghofrani, W Seeger, F Grimminger, RT Schermuly, N Weissmann · Pneumologie · Ausgabe 05/2012

DOI 10.1055/s-0032-1315540

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Autor:innenF Veit, B Egemnazarov, M Roth, D Kosanovic, O Pak, HA Ghofrani, W Seeger, F Grimminger, RT Schermuly, N Weissmann
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Chronic alveolar hypoxia induces pulmonary hypertension (PH) and pulmonary vascular remodeling. Reactive oxygen species (ROS) are thought to play a major role in this process. Recent findings suggested that ROS production by NADPH oxidase 4 (Nox4) is plays an important role for PH development in hypoxia-induced PH in mice and human idiopathic pulmonary arterial hypertension (IPAH). Against this background we investi…

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F Veit, B Egemnazarov, M Roth, D Kosanovic, O Pak, HA Ghofrani, W Seeger, F Grimminger, RT Schermuly, N Weissmann (2012) Function of NADPH oxidase 1 in pulmonary arterial smooth muscle cells from monocrotaline-induced pulmonary hypertension. Pneumologie (05). https://doi.org/10.1055/s-0032-1315540

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