CareLit · DOI-Nachweis · Pneumologie
Inhibition of mucociliary clearance by anesthetics is independent of the two-pore-domain K+-channel, TASK-1, in the mouse trachea
DOI 10.1055/s-0032-1315551
Bibliografische Angaben
Nachweis in CareLit
Autor:innenG Murtaza, P Faulhammer, A Goldenberg, R Paddenberg, U Pfeil, W Kummer
ZeitschriftPneumologie
Ausgabe05/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Volatile anesthetics inhibit airway mucociliary clearance. One of their molecular targets is the two-pore-domain K+-channel, TASK-1, in that they increase its open probability. The present study aimed to clarify whether TASK-1 regulates cilia-driven mucociliary clearance in the mouse trachea utilizing particle transport speed (PTS) at the mucosal surface as readout. Tracheas from TASK-1 gene-deficient mice and corre…
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Zitierempfehlung
G Murtaza, P Faulhammer, A Goldenberg, R Paddenberg, U Pfeil, W Kummer (2012) Inhibition of mucociliary clearance by anesthetics is independent of the two-pore-domain K+-channel, TASK-1, in the mouse trachea. Pneumologie (05). https://doi.org/10.1055/s-0032-1315551
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