CareLit · DOI-Nachweis · Klinische Pädiatrie
Effects of histone methyltransferase inhibitor 3-Deazaneoplanocin (DZNep) on rhabdoid tumor cell lines
DOI 10.1055/s-0032-1320170
Bibliografische Angaben
Nachweis in CareLit
Autor:innenC Borchardt, R Unland, D Clemens, K Kerl, G Hempel, MC Frühwald
ZeitschriftKlinische Pädiatrie
Ausgabe11/2012
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Rhabdoid tumors (RT) are highly aggressive pediatric tumors which arise in brain, heart, kidney, liver and other soft tissues. Although the prognosis of RT patients has improved, it still remains poor due to an initial response to conventional chemotherapy followed by resistance. Rhabdoid tumors are characterized by mutations in genes of the SWI/SNF chromatin remodeling complex, most often biallelic inactivation of…
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Zitierempfehlung
C Borchardt, R Unland, D Clemens, K Kerl, G Hempel, MC Frühwald (2012) Effects of histone methyltransferase inhibitor 3-Deazaneoplanocin (DZNep) on rhabdoid tumor cell lines. Klinische Pädiatrie (11). https://doi.org/10.1055/s-0032-1320170
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